Weight variation in patients with haematological malignancies based on biochemical markers. ANOVA analysis
DOI:
https://doi.org/10.55204/trc.v4i2.e376Keywords:
Hematological neoplasm, weight variation, biochemical markers, patients, nutritional managementAbstract
Hematological neoplasms, which include leukemias, lymphomas, and myelomas, affect the cloning of hematopoietic cells and have a significant impact on various populations worldwide. Weight variation in patients with these diseases is a crucial clinical phenomenon, as it influences comorbidities and disease treatments, reflecting both the nutritional status and the activity of the pathology and response to treatment. Biochemical markers such as glucose, urea, creatinine, total proteins, serum albumin, prealbumin, vitamin D, phosphorus, magnesium, AST/GOT, ALT/GPT, cholesterol, HDL, triglycerides, hemoglobin, and hematocrit are valuable tools for assessing this variation. In this study, a retrospective longitudinal quantitative approach was adopted to analyze the relationship between these markers and weight variation in 62 patients with hematological neoplasms, using one-way ANOVA. The results indicated that levels of total proteins, phosphorus, GPT, and HCT decrease with weight loss, while iron levels increase. These findings suggest that certain biochemical markers can act as predictors of weight variation, which could optimize nutritional management and treatment strategies, improving patients' quality of life and reducing morbidity and mortality rates. The research underscores the need for future studies to include additional variables such as inflammatory markers and physical activity to find more sensitive predictors of weight variation in this population.
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