Acute Pulmonary Thromboembolism as a diagnostic challenge: Case report
DOI:
https://doi.org/10.55204/trc.v3i2.e240Keywords:
Thromboembolism, Respiratory Insufficiency, Echocardiography, Diabetic KetoacidosisAbstract
Introduction: Pulmonary thromboembolism is considered a cardiovascular emergency that entails high morbidity and mortality in hospitalized patients. Its incidence is high, approximately 100 to 200 cases per 100 thousand inhabitants. The clinical presentation of the patient is generally the presence of dyspnea. For its diagnosis, clinical prediction scales are used, among them, the most used is the Wells scale.
Case presentation: We present the case of an elderly patient, bedridden, with inadequate control of his underlying diseases who was admitted due to decompensation of type 2 diabetes mellitus and who quickly evolved into respiratory failure and hemodynamic instability without apparent cause. Based on his clinical symptoms and together with the complementary tests that were performed, in addition to the use of the Wells scale with a high score, a fulminant pulmonary thromboembolism was diagnosed. Despite all the measures available that could be used to stabilize the patient, a satisfactory result was not achieved, resulting in his death.
Conclusions: The primary risk factor for PE is the presence of deep vein thrombosis. A timely diagnosis and adequate treatment, as well as the individualization of each case to provide the most appropriate therapy to safeguard the patient's life.
Downloads
References
Arias-Rodríguez Fabián D., Armijos-Quintero Daniel A., Beltrán-Vinueza Pamela A., Córdova-Macías Daniela V., Guadamud-Loor Jorge X., Osejos-Moreira Walter D. et al . Diagnóstico y tratamiento de tromboembolia pulmonar. Revisión bibliográfica. Rev. mex. angiol. [revista en la Internet]. 2022 Sep [citado 2023 Sep 16] ; 50( 3 ): 96-109. Disponible en: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S2696-130X2022000300096&lng=es. Epub 13-Oct-2022. https://doi.org/10.24875/rma.22000018.
Paizano Vanega G, Zúñiga EF, Bonilla DV. Diagnostico de troboembolismo pulmonar agudo. Rev Medica Sinerg. 2022;7(2):757-9.
Piñar Sancho G, Abarca Zúñiga V, Moya Corea S. Diagnóstico y manejo actualizado del tromboembolismo pulmonar agudo. Rev.méd.sinerg. [Internet]. 1 de enero de 2021 [citado 16 de septiembre de 2023];6(1):e633. Disponible en: https://revistamedicasinergia.com/index.php/rms/article/view/633
Megyeri B, Christe A, Schindera ST, Horkay E, Sikula J, Cullmann JL, et al. Accuracy of computed tomography angiography in the detection of pulmonary embolism in patients with high body weight. Eur J Intern Med. 2014;25(8):724-30.
Nicholson M, Chan N, Bhagirath V, Ginsberg J. Prevention of Venous Thromboembolism in 2020 and Beyond. J Clin Med. 2020;9(8):2467.
Kucher et al. Randomized, Controlled Trial of Ultrasound-Assisted Catheter-Directed Thrombolysis for Acute intermediate Risk Pulmonary Embolism. Circulation. 2014;129: páginas 479-486. https://doi.org/10.1161/CIRCULATIONAHA.113.0055443.
Martínez-González, Mayra; Castañón-González JA. Enfermedad tromboembólica venosa en la unidad de cuidados intensivos. Rev Médica IMSS. 2001;40(3):233–45.
Kearon C. Diagnosis of suspected venous thromboembolism. Hematology. 2016;2016(1):397-403.
Jiménez Sánchez N. Tromboembolismo pulmonar:: Abordaje, diagnóstico y manejo. CS [Internet]. 18 de octubre de 2021 [citado 16 de septiembre de 2023];5(5):Pág. 7-18. Disponible en: https://revistacienciaysalud.ac.cr/ojs/index.php/cienciaysalud/article/view/267
Kearon C, de Wit K, Parpia S, Schulman S, Afilalo M, Hirsch A, et al. Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability. N Engl J Med. 2019;381(22):2125-34
Jiménez D, Yusen RD. Prognostic models for selecting patients with acute pulmonary embolism for initial outpatient therapy. Curr Opin Pulm Med 2008; 14: 414-21.
Lim W, Le Gal G, Bates SM, Righini M, Haramati LB, Lang E, et al. American Society of Hematology 2018 guidelines for management of venous thromboembolism: diagnosis of venous thromboembolism. Blood Adv. 2018;2(22):3226-56.
Jiménez D, Aujesky D, Moores L, Gómez V, Lobo JL, Uresandi F, et al. Simplification of the Pulmonary Embolism Severity Index for Prognostication in Patients With Acute Symptomatic Pulmonary Embolism. Arch Intern Med 2010; 170: 1383-9.
Jorge S, Florenzano M. DIAGNÓSTICO Y TRATAMIENTO DEL TROMBOEMBOLISMO PULMONAR. Rev Médica Clínica Las Condes. 2015;26(3):338-43
Lucena Romero Joaquín, Laborda Gálvez José L, Rodríguez González Lucía. Tromboembolismo pulmonar como causa de muerte súbita inesperada en personas de 1-35 años. CorSalud. 2017 ;9(3):215-217
Machado VL, Dimakis RDA. Enfoque diagnóstico de la tromboembolia pulmonar. Acta Med. 2017;15(1):36-46. doi:10.35366/70733.
Galiè, N., Hoeper, N., Humbert, M., Torbicki T. Guidelines for the diagnosis and treatment of pulmonary hypertension. European Respiratory Journal. 2019;34(6):1219–1263. DOI: 10.1183/09031936.00139009
Thompson, B. T., Kabrhel, C., & Peña, C. Clinical presentation, evaluation, and diagnosis of the nonpregnant adult with suspected acute pulmonary embolism. UpToDate. 2022. https://www.uptodate.com/contents/clinical-presentation-evaluation-and-diagnosis-of-the-nonpregnant-adult-with-suspected-acute-pulmonary-embolismsectionName=CLINICAL20PRESENTATION&search=pulmonary%20thromboembolism&topicRef=8253&anchor=H456585787&source=see_link#H4565857879.
Raja, A., Greenberg, J., Qaseem, A., Denberg, T., Fitterman, N., & Schuur, J. Evaluation of Patients With Suspected Acute Pulmonary Embolism: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians. Annals Of Internal Medicine. 2015;163(9):701–11. https://doi.org/10.7326/M14-177210.
Di Marca, S., Cilia, C., Campagna, A. Comparison of Wells and Revised Geneva Rule to Assess Pretest Probability of Pulmonary Embolism in High-Risk Hospitalized Elderly Adults. Journal of The American Geriatric Society. 2015;63(6):1091–1097. https://doi.org/10.1111/jgs.1345911
Weekes, A., Thacker, G., Troha, D., Johnson, A., Chanler-Berat, J., Norton, H., Runyon, M. Diagnostic Accuracy of Right Ventricular Dysfunction Markers in Normotensive Emergency Department Patients With Acute Pulmonary Embolism. Ann Emerg Med. 2016;68(3):277–91. https://doi.org/10.1016/j.annemergmed.2016.01.027
Farm, M., Siddiqui, A., Onelöv, L., Järnberg, I., Eintrei, J. Age-adjusted D-dimer cut-off leads to more efficient diagnosis of venous thromboembolism in the emergency department: a comparison of four assays. Journal of Thrombosis and Haemostasis. 2018;16(5):866–875. https://doi.org/10.1111/jth.13994.
Shopp, J., Stewart, L., Emmett, T., & Kline, J. Findings From 12-lead Electrocardiography That Predict Circulatory Shock From Pulmonary Embolism: Systematic Review and Meta-analysis. Academic Emergency Medicine. 2015;22(10):1127–1137. https://doi.org/10.1111/acem.12769
Barco, S., Ende-Verhaar, Y., C, B., Jimenez, D., Lankeit, M., Huisman, M., Konstantinides, S., & Klok, F. Differential impact of syncope on the prognosis of patients with acute pulmonary embolism: a systematic review and meta-analysis. European Heart Journal. 2018;39(47):4186–4195. https://doi.org/10.1093/eurheartj/ehy631
Duffett L, Castellucci LA, Forgie MA. Pulmonary embolism: update on management and controversies. BMJ. 2020;370:m2177. https://doi.org/10.1136/bmj.m2177.
Konstantinides, S., Meyer, G., Becattini, C., Bueno, H. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC). European Heart Journal. 2020;41(4):543–603. https://doi.org/10.1093/eurheartj/ehz405.
Miranda GLH, Linares RG, Robaina DS, León R de la CR. Análisis de la producción científica sobre uso de la ecografía en la reanimación cardiopulmonar en Scopus. Data & Metadata 2023;2:37. https://doi.org/10.56294/dm202337.
Downloads
Published
Issue
Section
License
Copyright (c) 2023 Jose Freddy Villa Pallashco, Jennifer Marisol Fernandez Leon, Mauricio Xavier Barrera Saguay, Katherine Daniela Minda Mejía, Angélica Fernanda Sasaguay Parapi, Bryam Alfredo Sanchez Peralta, Bruno Mateo Aray Coellar

This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors retain the moral and patrimonial rights of their works. They only give to the magazine Tesla Revista Científica the right to the first publication of this. Since Tesla Revista Científica is an open access publication, readers can fully or partially reproduce its content as long as they properly credit the corresponding authors and the journal itself. Tesla Revista Científica undertakes not to make commercial use of the texts it receives and/or publishes.
Our journal is governed by the international policies SHERPA/RoMEO: Green journal: They allow the self-archiving of both the pre-print (draft of a paper) and the post-print (the version corrected and reviewed by peers) and even the final version ( layout as it will be published in the journal).
See also "Copyright and licences".











