Fitoterapia en Osteoartritis: Eficacia y mecanismos implicados
DOI:
https://doi.org/10.55204/trc.v3i1.e143Palabras clave:
Fitoreapia, mecanismos moleculares, inflamación, estrés oxidativo, cartílago, vía de señalizaciónResumen
La Osteoartritis es una patología degenerativa inflamatoria crónica multifactorial, que afecta a las articulaciones, los principales mecanismos implicados en su progresión incluyen inflamación, estrés oxidativo y consecuente degradación del cartílago, lo cual conduce a alteraciones histológicas progresivas y manifestación de síntomas incapacitantes en el paciente. El tratamiento convencional incluye desde analgésicos hasta agentes biológicos, los cuales solo brindan un alivio temporal y frecuentemente se asocian con efectos adversos, mayor índice de toxicidad. Por lo cual fitoterápicos como la cúrcuma, la Boswellia Serrata, la Harpagophytum Procumbens, el Jengibre, el Té verde y la Iicariina han ido cobrando un papel importante en el área reumatológica gracias a sus propiedades condroprotectoras, antinflamatorias, analgésicas y antioxidantes mediante la regulación de varias vías implicadas.
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