Doppler de arterias uterinas para tamizaje y prevención de preeclampsia
DOI:
https://doi.org/10.55204/trc.v3i1.e119Palabras clave:
Ultrasonografía Doppler, arteria uterina, diagnostico, pre eclampsiaResumen
Introducción: La preeclampsia sigue siendo una de las patologías más frecuentes en el embarazo con una alta tasa de morbilidad y mortalidad tanto materna como fetal, sin embargo, las técnicas de ecografía Doppler han sido de gran ayuda en los últimos años y han permitido reconocer tempranamente cambios patológicos producidos en el feto frente a diferentes tipos de lesión, dejando que actúe de forma oportuna en la disminución de la de morbilidad y mortalidad neonatal.
Objetivos: Describir la utilidad de la ecografía Doppler de las arterias uterinas para el tamizaje y prevención de preeclampsia
Métodos: Se llevó a cabo una búsqueda sistemática de la bibliografía en las principales bibliotecas medicas electrónicas (PUBMED, Cochrane Library, Web of Science, Trip Database) en los últimos 15 años a partir de octubre del 2007 hasta Octubre del 2022 en humanos, utilizando términos DeCS y MeSH como: ultrasonography, doppler, uterine artery, diagnosis, screening y pre-eclampsia,
Resultados: Se incluyeron 28 revisiones bibliográficas, en donde constan: 11 ensayos clínicos, 5 revisiones, 5 estudios observacionales, 3 soportes de investigación, 2 metaanálisis, 1 estudio comparativo y 1 estudio de evaluación, que abarco todos los tipos de estudios.
Conclusión: La ecografía Doppler de las arterias uterinas combinado con marcadores maternos aumentan la tasa de detección de pre eclampsia, es una herramienta diagnóstica útil en las gestantes, mostrando así una mayor capacidad predictiva en el tamizaje de preeclampsia, disminuyendo de manera importante los procedimientos invasivos.
Palabras clave: Ultrasonografía Doppler, arteria uterina, diagnostico, pre eclampsia.
Descargas
Referencias
Roberts J, Agosto P, Bakris G, Barton J, Bernstein I, Druzin M, et al. Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy. Obstetrics and gynecology [Internet]. 2013 Nov;122(5):1122–31. Available from: https://journals.lww.com/greenjournal/Fulltext/2013/11000/Hypertension_in_Pregnancy__Executive_Summary.36.aspx
Huppertz B. Placental origins of preeclampsia: challenging the current hypothesis. Hypertension [Internet]. 2008 Apr 1;51(4 PART 2 SUPPL.):970–5. Available from: https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.107.107607?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub 0pubmed
Poon LCY, Kametas NA, Chelemen T, Leal A, Nicolaides KH. Maternal risk factors for hypertensive disorders in pregnancy: A multivariate approach. J Hum Hypertens [Internet]. 2010 Jun 11;24(2):104–10. Available from: https://www.nature.com/articles/jhh200945
Angeli F, Angeli E, Reboldi G, Verdecchia P. Hypertensive disorders during pregnancy: Clinical applicability of risk prediction models. J Hypertens [Internet]. 2011;29(12):2320–3. Available from: https://journals.lww.com/jhypertension/Fulltext/2011/12000/Hypertensive_disorders_during_pregnancy__clinical.7.aspx
Myatt L, Clifton RG, Roberts JM, Spong CY, Hauth JC, Varner MW, et al. First-Trimester Prediction of Preeclampsia in Low-Risk Nulliparous Women. Obstetrics and Gynecology [Internet]. 2012 Jun;119(6):1234. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360523/
Comite. First-Trimester Risk Assessment for Early-Onset Preeclampsia. Obstetrics & Gynecology [Internet]. 2015 Sep;126(3):e25–7. Available from: https://journals.lww.com/greenjournal/Fulltext/2015/09000/Committee_Opinion_No__638__First_Trimester_Risk.49.aspx
Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, Yu KF, et al. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med [Internet]. 2004 Feb 12;350(7):672–83. Available from: https://www.nejm.org/doi/pdf/10.1056/NEJMoa031884?articleTools=true
Kusanovic JP, Romero R, Chaiworapongsa T, Mittal P, Vaisbuch E, Mazaki-Tovi S, et al. A Prospective Cohort Study of the Value of Maternal Plasma Concentrations of Angiogenic and Anti-angiogenic Factors in Early Pregnancy and Midtrimester in the Identification of Patients Destined to Develop Preeclampsia. J Matern Fetal Neonatal Med [Internet]. 2009;22(11):1021–38. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427777/pdf/nihms396421.pdf
Foidart JM, Munaut C, Chantraine F, Akolekar R, Nicolaides KH. Maternal plasma soluble endoglin at 11-13 weeks’ gestation in preeclampsia. Ultrasound in Obstetrics and Gynecology [Internet]. 2010 Jun;35(6):680–7. Available from: https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1002/uog.7621
Thadhani R, Mutter WP, Wolf M, Levine RJ, Taylor RN, Sukhatme VP, et al. First trimester placental growth factor and soluble fms-like tyrosine kinase 1 and risk for preeclampsia. J Clin Endocrinol Metab [Internet]. 2004 Feb;89(2):770–5. Available from: https://pubmed.ncbi.nlm.nih.gov/14764795/
Gonen R, Shahar R, Grimpel YI, Chefetz I, Sammar M, Meiri H, et al. Placental protein 13 as an early marker for pre-eclampsia: a prospective longitudinal study. BJOG [Internet]. 2008 Nov;115(12):1465–72. Available from: https://pubmed.ncbi.nlm.nih.gov/19035985/
Spencer K, Cowans NJ, Chefetz I, Tal J, Meiri H. First-trimester maternal serum PP-13, PAPP-A and second-trimester uterine artery Doppler pulsatility index as markers of pre-eclampsia. Ultrasound Obstet Gynecol [Internet]. 2007 Feb;29(2):128–34. Available from: https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1002/uog.3876
Burger O, Pick E, Zwickel J, Klayman M, Meiri H, Slotky R, et al. Placental protein 13 (PP-13): effects on cultured trophoblasts, and its detection in human body fluids in normal and pathological pregnancies. Placenta [Internet]. 2004 Aug 1;25(7):608–22. Available from: https://www.sciencedirect.com/science/article/abs/pii/S014340040400013X?via%3Dihub
Shaarawy M, Abdel-Magid AMA. Plasma endothelin-1 and mean arterial pressure in the prediction of pre-eclampsia. International Journal of Gynecology & Obstetrics [Internet]. 2000 Feb 1;68(2):105–11. Available from: https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1016/S0020-7292%2899%2900180-0
Bosio PM, Cannon S, McKenna PJ, O’Herlihy C, Conroy R, Brady H. Plasma P-selectin is elevated in the first trimester in women who subsequently develop pre-eclampsia. BJOG [Internet]. 2001 Jul;108(7):709–15. Available from: https://pubmed.ncbi.nlm.nih.gov/11467696/
Pilalis A, Souka AP, Antsaklis P, Daskalakis G, Papantoniou N, Mesogitis S, et al. Screening for pre-eclampsia and fetal growth restriction by uterine artery Doppler and PAPP-A at 11-14 weeks’ gestation. Ultrasound Obstet Gynecol [Internet]. 2007 Feb;29(2):135–40. Available from: https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1002/uog.3881
Yu CKH, Khouri O, Onwudiwe N, Spiliopoulos Y, Nicolaides KH. Prediction of pre-eclampsia by uterine artery Doppler imaging: relationship to gestational age at delivery and small-for-gestational age. Ultrasound in Obstetrics and Gynecology [Internet]. 2008 Mar 1;31(3):310–3. Available from: https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.5252
Editores. Thieme E-Books & E-Journals - American Journal of Perinatology / Issue [Internet]. 2022. Available from: https://www.thieme-connect.com/products/ejournals/journal/10.1055/s-00000009
D’Anna R, Baviera G, Giordano D, Todarello G, Corrado F, Buemi M. Second trimester neutrophil gelatinase-associated lipocalin as a potential prediagnostic marker of preeclampsia. Acta Obstet Gynecol Scand [Internet]. 2008;87(12):1370–3. Available from: https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1080/00016340802464463
Sibai B, Romero R, Klebanoff MA, Rice MM, Caritis S, Hauth J, et al. Maternal plasma concentrations of the soluble tumor necrosis factor receptor 2 are increased prior to the development of preeclampsia. Am J Obstet Gynecol [Internet]. 2009;(6):630. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862352/pdf/nihms156490.pdf
Lynch AM, Msph B, Murphy JR, Byers T, Gibbs RS, Neville MC, et al. Alternative complement pathway activation fragment Bb in early pregnancy as a predictor of preeclampsia. Am J Obstet Gynecol [Internet]. 2008;198(4):385–6. Available from: ncbi.nlm.nih.gov/pmc/articles/PMC2362503/pdf/nihms40061.pdf
Enquobahrie DA, Williams MA, Butler CL, Frederick IO, Miller RS, Luthy DA. Maternal Plasma Lipid Concentrations in Early Pregnancy and Risk of Preeclampsia. 2004; Available from: https://pubmed.ncbi.nlm.nih.gov/15233976/#:~:text=Results%3A Women who subsequently developed,in control subjects (P %3C.
Bersinger NA, Ødegård RA. Second- and third-trimester serum levels of placental proteins in preeclampsia and small-for-gestational age pregnancies. Acta Obstet Gynecol Scand [Internet]. 2004 Jan;83(1):37–45. Available from: https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1111/j.1600-0412.2004.00277.x
Farzadnia M, Ayatollahi H, Hasan-zade M, Rahimi HR. A Comparative Study of Serum Level of Vascular Cell Adhesion Molecule-1 (sVCAM-1), Intercellular Adhesion Molecule-1(ICAM-1) and High Sensitive C - reactive protein (hs-CRP) in Normal and Pre-eclamptic Pregnancies. Iran J Basic Med Sci [Internet]. 2013 May;16(5):689. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700043/pdf/ijbms-16-689.pdf
Clausen T, Djurovic S, Henriksen T. Dyslipidemia in early second trimester is mainly a feature of women with early onset pre-eclampsia. BJOG [Internet]. 2001 Oct 1;108(10):1081–7. Available from: https://onlinelibrary.wiley.com/doi/full/10.1111/j.1471-0528.2001.00247.x
Madazli R, Kuseyrioglu B, Uzun H, Uludag S, Ocak V. Prediction of preeclampsia with maternal mid-trimester placental growth factor, activin A, fibronectin and uterine artery Doppler velocimetry. Int J Gynaecol Obstet [Internet]. 2005;89(3):251–7. Available from: https://pubmed.ncbi.nlm.nih.gov/15919391/
Li X, Shen L, Tan H. Polymorphisms and Plasma Level of Transforming Growth Factor-Beta 1 and Risk for Preeclampsia: A Systematic Review. PLoS One [Internet]. 2014 May 13;9(5). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019528/
Chappell LC, Seed PT, Briley A, Kelly FJ, Hunt BJ, Charnock-Jones DS, et al. A longitudinal study of biochemical variables in women at risk of preeclampsia. Am J Obstet Gynecol [Internet]. 2002 Jul 1;187(1):127–36. Available from: https://www.ajog.org/article/S0002-9378(02)00093-5/fulltext
Grobman WA, Kazer RR. Serum insulin, insulin-like growth factor-I, and insulin-like growth factor binding protein-1 in women who develop preeclampsia. Obstetrics and gynecology [Internet]. 2001;97(4):521–6. Available from: https://pubmed.ncbi.nlm.nih.gov/11275021/
Martínez A. MARCADORES BIOQUÍMICOS PREDICTORES DE PREECLAMPSIA [Internet]. Asociación española del laboratorio clínico; 2014 [cited 2022 Oct 29]. Available from: https://www.aefa.es/wp-content/uploads/2014/08/Trabajo_completo.pdf
Scazzocchio E, Oros D, Diaz D, Ramirez JC, Ricart M, Meler E, et al. Impact of aspirin on trophoblastic invasion in women with abnormal uterine artery Doppler at 11–14 weeks: a randomized controlled study. Ultrasound in Obstetrics and Gynecology [Internet]. 2017 Apr 1;49(4):435–41. Available from: https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1002/uog.17351
Gallo DM, Wright D, Casanova C, Campanero M, Nicolaides KH. Competing risks model in screening for preeclampsia by maternal factors and biomarkers at 19-24 weeks’ gestation. Am J Obstet Gynecol [Internet]. 2016 May 1;214(5):619.e1-619.e17. Available from: https://www.ajog.org/article/S0002-9378(15)02345-5/fulltext
Razik MA, El-Berry S, Abosereah M, Edris Y, Sharafeldeen A. Prophylactic treatment for preeclampsia in high-risk teenage primigravidae with nitric oxide donors: a pilot study. Revista de medicina materno-fetal y neonatal [Internet]. 2016 Aug 17;29(16):2617–20. Available from: https://www-tandfonline-com.vpn.ucacue.edu.ec/doi/abs/10.3109/14767058.2015.1094793
Park F, Russo K, Williams P, Pelosi M, Puddephatt R, Walter M, et al. Prediction and prevention of early-onset pre-eclampsia: impact of aspirin after first-trimester screening. Ultrasound in Obstetrics & Gynecology [Internet]. 2015 Oct 1;46(4):419–23. Available from: https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.14819
Savasan ZA, Goncalves LF, Bahado-Singh RO. Second- and third-trimester biochemical and ultrasound markers predictive of ischemic placental disease. Semin Perinatol [Internet]. 2014 Apr 1;38(3):167–76. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0146000514000184?via%3Dihub
Souza E v., Torloni MR, Atallah AN, dos Santos GMS, Kulay L, Sass N. Aspirin plus calcium supplementation to prevent superimposed preeclampsia: a randomized trial. Brazilian Journal of Medical and Biological Research [Internet]. 2014;47(5):419. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075311/
Verlohren S, Melchiorre K, Khalil A, Thilaganathan B. Uterine artery Doppler, birth weight and timing of onset of pre-eclampsia: providing insights into the dual etiology of late-onset pre-eclampsia. Ultrasound in Obstetrics & Gynecology [Internet]. 2014 Sep 1;44(3):293–8. Available from: https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.13310
Schleussner E, Lehmann T, Kähler C, Schneider U, Schlembach D, Groten T. Impact of the nitric oxide-donor pentaerythrityltetranitrate on perinatal outcome in risk pregnancies: A prospective, randomized, double-blinded trial. J Perinat Med [Internet]. 2014 Jul 1;42(4):507–14. Available from: https://www.degruyter.com/document/doi/10.1515/jpm-2013-0212/html
Weissgerber TL, McGee PL, Myatt L, Hauth JC, Varner MW, Wapner RJ, et al. Haptoglobin Phenotype and Abnormal Uterine Artery Doppler in a Racially Diverse Cohort. J Matern Fetal Neonatal Med [Internet]. 2014 Nov 1;27(17):1728. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096612/
Polsani S, Phipps E, Jim B. Emerging New Biomarkers of Preeclampsia. Adv Chronic Kidney Dis [Internet]. 2013 May 1;20(3):271–9. Available from: https://www.ackdjournal.org/article/S1548-5595(13)00002-5/fulltext
Villa PM, Kajantie E, Räikkönen K, Pesonen AK, Hämäläinen E, Vainio M, et al. Aspirin in the prevention of pre-eclampsia in high-risk women: a randomised placebo-controlled PREDO Trial and a meta-analysis of randomised trials. BJOG [Internet]. 2013 Jan 1;120(1):64–74. Available from: https://obgyn.onlinelibrary.wiley.com/doi/10.1111/j.1471-0528.2012.03493.x
Myatt L, Clifton RG, Roberts JM, Spong CY, Hauth JC, Varner MW, et al. The Utility of Uterine Artery Doppler Velocimetry in Prediction of Preeclampsia in a Low-Risk Population. Obstetrics and gynecology [Internet]. 2012 Oct;120(4):815. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449210/
Forest JC, Charland M, Massé J, Bujold E, Rousseau F, Lafond J, et al. Candidate biochemical markers for screening of pre-eclampsia in early pregnancy. Clin Chem Lab Med [Internet]. 2012 Jun 1;50(6):973–84. Available from: https://www.degruyter.com/document/doi/10.1515/cclm.2011.820/html
Nguyen NC, Evenson KR, Savitz DA, Chu H, Thorp JM, Daniels JL. Physical activity and maternal-fetal circulation measured by Doppler ultrasound. J Perinatol [Internet]. 2013 Feb;33(2):87. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459289/
Herraiz I, Escribano D, Gómez-Arriaga PI, Hernández-García JM, Herraiz MA, Galindo A. Predictive value of sequential models of uterine artery Doppler in pregnancies at high risk for pre-eclampsia. Ultrasound in Obstetrics & Gynecology [Internet]. 2012 Jul 1;40(1):68–74. Available from: https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.10147
Kuc S, Wortelboer EJ, van Rijn BB, Franx A, Visser GHA, Schielen PCJI. Evaluation of 7 serum biomarkers and uterine artery Doppler ultrasound for first-trimester prediction of preeclampsia: a systematic review. Obstet Gynecol Surv [Internet]. 2011 Apr;66(4):225–39. Available from: https://journals.lww.com/obgynsurvey/Abstract/2011/04000/Evaluation_of_7_Serum_Biomarkers_and_Uterine.21.aspx
Fox C, Khan K, Coomarasamy A. How to interpret randomised trials of test–treatment combinations: a critical evaluation of research on uterine Doppler test to predict, and aspirin to prevent, pre-eclampsia. BJOG [Internet]. 2010 Jun 1;117(7):801–8. Available from: https://obgyn.onlinelibrary.wiley.com/doi/10.1111/j.1471-0528.2010.02577.x
Bujold E, Morency AM, Roberge S, Lacasse Y, Forest JC, Giguère Y. Acetylsalicylic Acid for the Prevention of Preeclampsia and Intra-uterine Growth Restriction in Women with Abnormal Uterine Artery Doppler: A Systematic Review and Meta-analysis. Journal of Obstetrics and Gynaecology Canada [Internet]. 2009 Sep 1;31(9):818–26. Available from: https://www.sciencedirect.com/science/article/abs/pii/S1701216316343006?via%3Dihub
Plasencia W, Maiz N, Poon L, Yu C, Nicolaides KH. Uterine artery Doppler at 11 + 0 to 13 + 6 weeks and 21 + 0 to 24 + 6 weeks in the prediction of pre-eclampsia. Ultrasound in Obstetrics and Gynecology [Internet]. 2008 Aug 1;32(2):138–46. Available from: https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.5402
Melchiorre K, Wormald B, Leslie K, Bhide A, Thilaganathan B. First-trimester uterine artery Doppler indices in term and preterm pre-eclampsia. Ultrasound in Obstetrics and Gynecology [Internet]. 2008 Aug 1;32(2):133–7. Available from: https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.5400
Stampalija T, Gyte GM, Alfirevic Z. Utero‐placental Doppler ultrasound for improving pregnancy outcome. Cochrane Database Syst Rev [Internet]. 2010 Sep 8;2010(9). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164824/#:~:text=Doppler ultrasound uses sound waves,medical interventions might improve outcomes.
Cnossen JS, Morris RK, ter Riet G, Mol BWJ, van der Post JAM, Coomarasamy A, et al. Use of uterine artery Doppler ultrasonography to predict pre-eclampsia and intrauterine growth restriction: a systematic review and bivariable meta-analysis. CMAJ : Canadian Medical Association Journal [Internet]. 2008 Mar 3;178(6):701. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263112/
Hadker N, Garg S, Costanzo C, Miller JD, Foster T, van der Helm W, et al. Financial impact of a novel pre-eclampsia diagnostic test versus standard practice: a decision-analytic modeling analysis from a UK healthcare payer perspective. Revista de economía medica [Internet]. 2010 Dec;13(4):728–37. Available from: https://www-tandfonline-com.vpn.ucacue.edu.ec/doi/full/10.3111/13696998.2010.535285
Kılıç F, Kayadibi Y, Yüksel MA, Adaletli İ, Ustabaşıoğlu FE, Öncül M, et al. Shear wave elastography of placenta: in vivo quantitation of placental elasticity in preeclampsia. Diagnostic and Interventional Radiology [Internet]. 2015;21(3):202. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463268/
García B, Llurba E, Valle L, Gómez-Roig MD, Juan M, Pérez-Matos C, et al. Do knowledge of uterine artery resistance in the second trimester and targeted surveillance improve maternal and perinatal outcome? UTOPIA study: a randomized controlled trial. Ultrasound in Obstetrics & Gynecology [Internet]. 2016 Jun 1;47(6):680–9. Available from: https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.15873
Murtoniemi K, Villa PM, Matomäki J, Keikkala E, Vuorela P, Hämäläinen E, et al. Prediction of pre-eclampsia and its subtypes in high-risk cohort: hyperglycosylated human chorionic gonadotropin in multivariate models. BMC Pregnancy Childbirth [Internet]. 2018 Jul 3;18(1). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029382/
Jurisic A, Jurisic Z, Lefkou E, Girardi G. Pravastatin plus L-arginine prevents adverse pregnancy outcomes in women with uteroplacental vascular dysfunction. Vascul Pharmacol [Internet]. 2021 Apr 1;137:106824. Available from: https://www.sciencedirect.com/science/article/pii/S1537189120303293?via%3Dihub
Tapp S, Guerby P, Girard M, Roberge S, Côté S, Ferreira E, et al. A Pilot Randomized Trial Comparing the Effects of 80 versus 160 mg of Aspirin on Midtrimester Uterine Artery Pulsatility Index in Women with a History of Preeclampsia. Journal of Obstetrics and Gynaecology Canada [Internet]. 2020 Dec 1;42(12):1498–504. Available from: https://www.jogc.com/article/S1701-2163(20)30488-6/fulltext
Martin AM, Bindra R, Curcio P, Cicero S, Nicolaides KH. Screening for pre-eclampsia and fetal growth restriction by uterine artery Doppler at 11–14 weeks of gestation. Ultrasound in Obstetrics and Gynecology [Internet]. 2001 Dec 1;18(6):583–6. Available from: https://obgyn.onlinelibrary.wiley.com/doi/abs/10.1046/j.0960-7692.2001.00594.x
Pedrosa AC, Matias A. Screening for pre-eclampsia: A systematic review of tests combining uterine artery Doppler with other markers. J Perinat Med [Internet]. 2011 Nov 1;39(6):619–35. Available from: https://www.degruyter.com/document/doi/10.1515/jpm.2011.077/html
Harrington K, Fayyad A, Thakur V, Aquilina J. The value of uterine artery Doppler in the prediction of uteroplacental complications in multiparous women. Ultrasound in Obstetrics and Gynecology [Internet]. 2004 Jan 1;23(1):50–5. Available from: https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.932
Oancea M, Grigore M, Ciortea R, Diculescu D, Bodean D, Bucuri C, et al. Uterine Artery Doppler Ultrasonography for First Trimester Prediction of Preeclampsia in Individuals at Risk from Low-Resource Settings. Medicina 2020, Vol 56, Page 428 [Internet]. 2020 Aug 26;56(9):428. Available from: https://www.mdpi.com/1648-9144/56/9/428/htm
Shahid N, Masood M, Bano Z, Naz U, Hussain SF, Anwar A, et al. Role of Uterine Artery Doppler Ultrasound in Predicting Pre-Eclampsia in High-Risk Women. Cureus [Internet]. 2021 Jul 9;13(7). Available from: https://www.cureus.com/articles/63351-role-of-uterine-artery-doppler-ultrasound-in-predicting-pre-eclampsia-in-high-risk-women
Spencer K, Yu CKH, Sawidou M, Papageorghiou AT, Nicolaides KH. Prediction of pre-eclampsia by uterine artery Doppler ultrasonography and maternal serum pregnancy-associated plasma protein-A, free β-human chorionic gonadotropin, activin A and inhibin A at 22 + 0 to 24 + 6 weeks’ gestation. Ultrasound in Obstetrics and Gynecology [Internet]. 2006 Jun 1;27(6):658–63. Available from: https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.2676
Onwudiwe N, Yu CKH, Poon LCY, Spiliopoulos I, Nicolaides KH. Prediction of pre-eclampsia by a combination of maternal history, uterine artery Doppler and mean arterial pressure. Ultrasound in Obstetrics and Gynecology [Internet]. 2008 Dec 1;32(7):877–83. Available from: https://onlinelibrary.wiley.com/doi/full/10.1002/uog.6124
Coomarasamy A, Papaioannou S, Gee H, Khan KS. Aspirin for the prevention of preeclampsia in women with abnormal uterine artery doppler: a meta-analysis. Obstetrics & Gynecology [Internet]. 2001 Nov 1;98(5):861–6. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0029784401015691
Publicado
Número
Sección
Licencia
Derechos de autor 2023 María José Rivera Mena, Andrés Mercado, Cisne Vega, Michelle Vanegas
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
Los autores conservan los derechos morales y patrimoniales de sus obras. Puesto que Tesla Revista Científica es una publicación de acceso abierto, los lectores pueden reproducir total o parcialmente su contenido siempre y cuando proporcionen adecuadamente el crédito a los autores correspondientes y a la revista misma. Tesla Revista Científica se compromete a no hacer uso comercial de los textos que recibe y/o publica.
Nuestra revista se rige por las politicas internacionales SHERPA/RoMEO: Revista verde: Permiten el autoarchivo tanto del pre-print (borrador de un trabajo) como del post-print (la versión corregida y revisada por pares) y hasta de la versión final (maquetada tal como saldrá publicada en la revista).
Véase también "Derechos de autor y licencias".
